Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms in PDLIM5 gene are associated with alcohol dependence, type 2 diabetes, and hypertension.

Journal of psychiatric research - 1 Jan 2017

Owusu Daniel, Pan Yue, Xie Changchun, Harirforoosh Sam, Wang Ke-Sheng

Abstract excerpt

The PDZ and LIM domain 5 (PDLIM5) gene may play a role in alcohol dependence (AD), bipolar disorder, and major depressive disorder; however, no study has identified shared genetic variants within PDLIM5 gene among AD, type 2 diabetes (T2D), and hypertension. This study investigated the association of 72 single nucleotide polymorphism (SNPs) with AD (1066 AD cases and 1278 controls) in the Study of Addiction -...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Alcoholism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Genome-Wide Association Study

Share to Hypertension

Share to LIM Domain Proteins

Share to Linkage Disequilibrium

Share to Logistic Models

Source

Identifiers

PMID: 27693979
DOI: 10.1016/j.jpsychires.2016.09.015

Genes

PDLIM5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in PDLIM5 gene are associated with alcohol dependence, type 2 diabetes, and hypertension.PMID 27693979Read ↗

Bayesian logistic regression in detection of gene-steroid interaction for cancer at PDLIM5 locus.Semantic proximity Read ↗

Gene expression and association analysis of LIM (PDLIM5) in major depressionSemantic proximity Read ↗

Positive association between the PDLIM5 gene and bipolar disorder in the Chinese Han population.Semantic proximity Read ↗

PDLIM5 and susceptibility to bipolar disorder: a family-based association study and meta-analysis.Semantic proximity Read ↗

Positive association between PDLIM5 and schizophrenia in the Chinese Han population.Semantic proximity Read ↗

A case-control association study of the PDLIM5 gene and bipolar disorder in a Sardinian sample.Semantic proximity Read ↗

Association of microRNA biogenesis pathway gene variants and alcohol dependence risk.Semantic proximity Read ↗

Serum miR-195-5p Exhibits Clinical Significance in the Diagnosis of Essential Hypertension with Type 2 Diabetes Mellitus by Targeting DRD1.Semantic proximity Read ↗

Nonsynonymous polymorphisms of the PDLIM5 gene association with the occurrence of both bipolar disorder and schizophrenia.Semantic proximity Read ↗

The potential effects of HECTD4 variants on fasting glucose and triglyceride levels in relation to prevalence of type 2 diabetes based on alcohol intake.Semantic proximity Read ↗

A major single nucleotide polymorphism of the PDLIM5 gene associated with recurrent major depressive disorder.Semantic proximity Read ↗

PDIA3 rs2788: An Independent Risk Factor for Hypertension and Its Interaction With Antihypertensive Medications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.