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Article

Innate immune defects in HIV permissive cell lines.

Retrovirology - 27 Jun 2016

Rausell Antonio, Muñoz Miguel, Martinez Raquel, Roger Thierry, Telenti Amalio, Ciuffi Angela

Abstract excerpt

BACKGROUND: Primary CD4+ T cells and cell lines differ in their permissiveness to HIV infection. Impaired innate immunity may contribute to this different phenotype. FINDINGS: We used transcriptome profiling of 1503 innate immunity genes in primary CD4+ T cells and permissive cell lines. Two clusters of differentially expressed genes were identified: a set of 249 genes that were highly expressed in primary cells...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27350062
DOI: 10.1186/s12977-016-0275-8
PMCID: PMC4924258

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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