Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HIV-1 Activates Macrophages Independent of Toll-Like Receptors

1 Dec 2008

Abstract excerpt

BACKGROUND: Macrophages provide an interface between innate and adaptive immunity and are important long-lived reservoirs for Human Immunodeficiency Virus Type-1 (HIV-1). Multiple genetic networks involved in regulating signal transduction cascades and immune responses in macrophages are coordinately modulated by HIV-1 infection. METHODOLOGY/PRINCIPAL FINDINGS: To evaluate complex interrelated processes and to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV/AIDS Research and Interventions
Share to HIV Research and Treatment
Share to Immune cells in cancer

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19048100
DOI: 10.1371/journal.pone.0003664

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HIV-1 Activates Macrophages Independent of Toll-Like ReceptorsPMID 19048100Read ↗

Macrophages and HIV-1Semantic proximity Read ↗

TLR7 and TLR8 activate distinct pathways in monocytes during RNA virus infectionSemantic proximity Read ↗

Macrophage activation and human immunodeficiency virus infection: HIV replication directs macrophages towards a pro-inflammatory phenotype while previous activation modulates macrophage susceptibility to infection and viral productionSemantic proximity Read ↗

Advances in macrophage and dendritic cell biology in HIV-1 infection stress key understudied areas in infection, pathogenesis, and analysis of viral reservoirsSemantic proximity Read ↗

Macrophages and HIV-1: An Unhealthy ConstellationSemantic proximity Read ↗

Macrophages and their relevance in Human Immunodeficiency Virus Type I infectionSemantic proximity Read ↗

Myeloid Cell Interaction with HIV: A Complex RelationshipSemantic proximity Read ↗

Human Immunodeficiency Virus Type 1-Induced Macrophage Gene Expression Includes the p21 Gene, a Target for Viral RegulationSemantic proximity Read ↗

Toll-like receptor expression and responsiveness are increased in viraemic HIV-1 infectionSemantic proximity Read ↗

HIV-1 Vpr combats the PU.1-driven antiviral response in primary human macrophagesSemantic proximity Read ↗

HIV and cells of macrophage/dendritic lineage and other non-T cell reservoirs: new answers yield new questionsSemantic proximity Read ↗

Monocyte to macrophage differentiation and changes in cellular redox homeostasis promote cell type-specific HIV latency reactivationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.