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Article

rugose (rg), a Drosophila A kinase anchor protein, is required for retinal pattern formation and interacts genetically with multiple signaling pathways.

Genetics - 1 Jun 2002

Shamloula Hoda K, Mbogho Mkajuma P, Pimentel Angel C, Chrzanowska-Lightowlers Zosia M A, Hyatt Vanneta, Okano Hideyuki, Venkatesh Tadmiri R

Abstract excerpt

In the developing Drosophila eye, cell fate determination and pattern formation are directed by cell-cell interactions mediated by signal transduction cascades. Mutations at the rugose locus (rg) result in a rough eye phenotype due to a disorganized retina and aberrant cone cell differentiation, which leads to reduction or complete loss of cone cells. The cone cell phenotype is sensitive to the level of rugose...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12072466
DOI: 10.1093/genetics/161.2.693
PMCID: PMC1462145

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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