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Article

Contextualizing Hepatocyte Functionality of Cryopreserved HepaRG Cell Cultures.

Drug metabolism and disposition: the biological fate of chemicals - 1 Sept 2016

Jackson Jonathan P, Li Linhou, Chamberlain Erica D, Wang Hongbing, Ferguson Stephen S

Abstract excerpt

Over the last decade HepaRG cells have emerged as a promising alternative to primary human hepatocytes (PHH) and have been featured in over 300 research publications. Most of these reports employed freshly differentiated HepaRG cells that require time-consuming culture (∼28 days) for full differentiation. Recently, a cryopreserved, predifferentiated format of HepaRG cells (termed here "cryo-HepaRG") has emerged...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27338863
DOI: 10.1124/dmd.116.069831
PMCID: PMC4998578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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