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Article

Mitral valve endothelial cells secrete osteoprotegerin during endothelial mesenchymal transition.

Journal of molecular and cellular cardiology - 1 Sept 2016

Songia Paola, Branchetti Emanuela, Parolari Alessandro, Myasoedova Veronika, Ferrari Giovanni, Alamanni Francesco, Tremoli Elena, Poggio Paolo

Abstract excerpt

AIMS: Mitral valve prolapse (MVP) has a prevalence of 3% in the general population, affecting >176 million people worldwide. Despite this, little is known about the molecular and cellular mechanisms involved in the progression of MVP and surgical intervention is the only available option. In this study we investigated the role of osteoprotegerin (OPG) during endothelial to mesenchymal transition (EndMT) in MVP....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27338002
DOI: 10.1016/j.yjmcc.2016.06.061
PMCID: PMC5026583

Genes

MVP

Provenance

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