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Article

RRM1 *151A>T, RRM1 -756T>C, and RRM1 -585T>Gis associated with increased susceptibility of lung cancer in Chinese patients.

Cancer medicine - 1 Aug 2016

Xu Xiao-Ling, Zheng Ji, Mao Wei-Min, Ling Zhi-Qiang

Abstract excerpt

Ribonucleotide reductase M1 (RRM1) is a crucial gene in DNA repair. Recent studies have shown that RRM1 expression can be a powerful predictor of survival or chemotherapy sensitivity in patients presenting with carcinomas who are treated with adjuvant gemcitabine-based chemotherapy including lung cancer. However, the relationship between the single nucleotide polymorphisms (SNP) of RRM1 and the susceptibility of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27335251
DOI: 10.1002/cam4.703
PMCID: PMC4971936

Genes

RRM1

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RRM1 *151A>T, RRM1 -756T>C, and RRM1 -585T>Gis associated with increased susceptibility of lung cancer in Chinese patients.PMID 27335251Read ↗

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