Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigation of some DNA repair genes association in non small cell lung cancer.

Cellular and molecular biology (Noisy-le-Grand, France) - 19 Dec 2015

Coskunpinar E, Yildiz P, Aynaci E, Turna A, Musteri Oltulu Y, Hekimoglu E, Isbir T, Yaylim I

Abstract excerpt

Ribonucleoside-diphosphate reductase subunit M2, also known as ribonucleotide reductase small subunit, is an enzyme that in humans is encoded by the RRM2 gene and also Ribonucleoside-diphosphate reductase large subunit is an enzyme that in humans is encoded by the RRM1 gene. RRM1 is a gene important in determining tumor phenotype, but also induced the expression of PTEN tumor suppressor gene, cell migration,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 8-Hydroxy-2'-Deoxyguanosine
Share to Carcinoma, Non-Small-Cell Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Deoxyguanosine

Share to DNA Repair

Share to Ribonucleoside Diphosphate Reductase

Share to Tumor Suppressor Proteins

Share to Xeroderma Pigmentosum Group D Protein

Source

Identifiers

PMID: 26718430

Genes

RRM1
ERCC2
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigation of some DNA repair genes association in non small cell lung cancer.PMID 26718430Read ↗

Association of genetic polymorphisms in DNA repair pathway genes with non-small cell lung cancer risk.Semantic proximity Read ↗

Single nucleotide polymorphisms of nucleotide excision repair pathway are significantly associated with outcomes of platinum-based chemotherapy in lung cancer.Semantic proximity Read ↗

Polymorphisms of DNA repair genes and risk of non-small cell lung cancer.Semantic proximity Read ↗

The genetic variations in DNA repair genes ERCC2 and XRCC1 were associated with the overall survival of advanced non-small-cell lung cancer patients.Semantic proximity Read ↗

Ribonucleotide reductase M2 (RRM2): Regulation, function and targeting strategy in human cancerSemantic proximity Read ↗

DNA Repair Gene Polymorphisms in Relation to Non-Small Cell Lung Cancer Survival.Semantic proximity Read ↗

Assoication of XRCC1 gene polymorphisms with risk of non-small cell lung cancer.Semantic proximity Read ↗

Potential Functional Variants in DNA Repair Genes Are Associated with Efficacy and Toxicity of Radiotherapy in Patients with Non-Small-Cell Lung CancerSemantic proximity Read ↗

Predictive value of ERCC1 and RRM1 gene single-nucleotide polymorphisms for first-line platinum- and gemcitabine-based chemotherapy in non-small cell lung cancer patients.Semantic proximity Read ↗

DNA repair in lung cancer: a large-scale quantitative analysis for polymorphisms in DNA repairing pathway genes and lung cancer susceptibility.Semantic proximity Read ↗

Association between single nucleotide polymorphisms (SNPs) and toxicity of advanced non-small-cell lung cancer patients treated with chemotherapy.Semantic proximity Read ↗

DNA repair pathway genes and lung cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.