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Article

Inner nuclear membrane protein Lem2 augments heterochromatin formation in response to nutritional conditions.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Aug 2016

Tange Yoshie, Chikashige Yuji, Takahata Shinya, Kawakami Kei, Higashi Masato, Mori Chie, Kojidani Tomoko, Hirano Yasuhiro, Asakawa Haruhiko, Murakami Yota, Haraguchi Tokuko, Hiraoka Yasushi

Abstract excerpt

Inner nuclear membrane proteins interact with chromosomes in the nucleus and are important for chromosome activity. Lem2 and Man1 are conserved members of the LEM-domain nuclear membrane protein family. Mutations of LEM-domain proteins are associated with laminopathy, but their cellular functions remain unclear. Here, we report that Lem2 maintains genome stability in the fission yeast Schizosaccharomyces pombe....

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Share to Chromatin Assembly and Disassembly
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 27334362
DOI: 10.1111/gtc.12385

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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