Article
Enho Mutations Causing Low Adropin: A Possible Pathomechanism of MPO-ANCA Associated Lung Injury.
EBioMedicine - 1 Jul 2016
Gao Feng, Fang Jun, Chen Falin, Wang Chengdang, Chen Shu, Zhang Sheng, Lv Xiaoting, Zhang Jinchi, He Qingliang, Weng Shaohuang, Liu Qicai, Lin Xin-Hua
Abstract excerpt
BACKGROUND: Myeloperoxidase (MPO) anti-neutrophil cytoplasm autoantibody (ANCA)-associated vasculitis commonly causes life-threatening pulmonary alveolar hemorrhage or fibrosis. Only a limited number of candidate gene variants have been explored, but hitherto, are not widely confirmed. In the present study, we investigated the importance of energy homeostasis associated gene (Enho) mutations and adropin...
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