Article
Lipid droplet-associated proteins are involved in the biosynthesis and hydrolysis of triacylglycerol in Mycobacterium bovis bacillus Calmette-Guerin.
The Journal of biological chemistry - 9 Jul 2010
Low Kai Leng, Shui Guanghou, Natter Klaus, Yeo Wee Kiang, Kohlwein Sepp D, Dick Thomas, Rao Srinivasa P S, Wenk Markus R
Abstract excerpt
Mycobacteria store triacylglycerols (TGs) in the form of intracellular lipid droplets (LDs) during hypoxia-induced nonreplicating persistence. These bacteria are phenotypically drug-resistant and therefore are believed to be the cause for prolonged tuberculosis treatment. LDs are also associated...
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