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Article

Comparison of small biopsy specimens and surgical specimens for the detection of EGFR mutations and EML4-ALK in non-small-cell lung cancer.

Oncotarget - 13 Sept 2016

Xiao DeSheng, Lu Can, Zhu Wei, He QiuYan, Li Yong, Fu ChunYan, Zhou JianHua, Liu Shuang, Tao YongGuang

Abstract excerpt

Epidermal growth factor receptor (EGFR) mutations and anaplastic lymphoma kinase (ALK) fusion genes represent novel oncogenes that are associated with non-small-cell lung cancers (NSCLC). The feasibility of detecting EGFR mutations and ALK fusion genes in small biopsy specimens or surgical specimens was determined. Of the 721 NSCLC patients, a total of 305 cases were positive for EGFR mutations (42.3%). The rate...

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Source

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Identifiers

PMID: 27322143
DOI: 10.18632/oncotarget.10011
PMCID: PMC5312294

Genes

EGFR
ALK
EML4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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