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Article

Outcomes of research biopsies in clinical trials of EGFR mutation-positive non-small cell lung cancer patients pretreated with EGFR-tyrosine kinase inhibitors.

Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Apr 2018

Liao Bin-Chi, Bai Ya-Ying, Lee Jih-Hsiang, Lin Chia-Chi, Lin Shu-Yung, Lee Yee-Fan, Ho Chao-Chi, Shih Jin-Yuan, Chang Yeun-Chung, Yu Chong-Jen, Chih-Hsin Yang James, Yang Pan-Chyr

Abstract excerpt

BACKGROUND/PURPOSE: Research biopsies (RBs) are crucial for developing novel molecular targeted agents. However, the safety and diagnostic yields of RBs have not been investigated in EGFR mutation-positive non-small cell lung cancer (NSCLC) patients pretreated with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs). METHODS: We searched the medical records of NSCLC patients who participated...

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PMID: 28499641
DOI: 10.1016/j.jfma.2017.04.018

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EGFR

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