Article
Phenotypic clustering: a novel method for microglial morphology analysis.
Journal of neuroinflammation - 17 Jun 2016
Verdonk Franck, Roux Pascal, Flamant Patricia, Fiette Laurence, Bozza Fernando A, Simard Sébastien, Lemaire Marc, Plaud Benoit, Shorte Spencer L, Sharshar Tarek, Chrétien Fabrice, Danckaert Anne
Abstract excerpt
BACKGROUND: Microglial cells are tissue-resident macrophages of the central nervous system. They are extremely dynamic, sensitive to their microenvironment and present a characteristic complex and heterogeneous morphology and distribution within the brain tissue. Many experimental clues highlight a strong link between their morphology and their function in response to aggression. However, due to their complex...
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