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Article

The Quest for Targets Executing MYC-Dependent Cell Transformation

2 Jun 2016

Abstract excerpt

MYC represents a transcription factor with oncogenic potential converting multiple cellular signals into a broad transcriptional response, thereby controlling the expression of numerous protein-coding and non-coding RNAs important for cell proliferation, metabolism, differentiation, and apoptosis. Constitutive activation of MYC leads to neoplastic cell transformation, and deregulated MYC alleles are frequently...

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Identifiers

PMID: 27313991
DOI: 10.3389/fonc.2016.00132

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The Quest for Targets Executing MYC-Dependent Cell TransformationPMID 27313991Read ↗

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