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Article

PTENpred: A Designer Protein Impact Predictor for PTEN-related Disorders.

Journal of computational biology : a journal of computational molecular cell biology - 1 Dec 2016

Johnston Sean B, Raines Ronald T

Abstract excerpt

Connecting a genotype with a phenotype can provide immediate advantages in the context of modern medicine. Especially useful would be an algorithm for predicting the impact of nonsynonymous single-nucleotide polymorphisms in the gene for PTEN, a protein that is implicated in most human cancers and connected to germline disorders that include autism. We have developed a protein impact predictor, PTENpred, that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27310656
DOI: 10.1089/cmb.2016.0058
PMCID: PMC5144848

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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