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Article

Interaction of a genetic risk score with physical activity, physical inactivity, and body mass index in relation to venous thromboembolism risk.

Genetic epidemiology - 1 Jun 2018

Kim Jihye, Kraft Peter, Hagan Kaitlin A, Harrington Laura B, Lindstroem Sara, Kabrhel Christopher

Abstract excerpt

INTRODUCTION: Venous thromboembolism (VTE) is highly heritable. Physical activity, physical inactivity and body mass index (BMI) are also risk factors, but evidence of interaction between genetic and environmental risk factors is limited. METHODS: Data on 2,134 VTE cases and 3,890 matched controls were obtained from the Nurses' Health Study (NHS), Nurses' Health Study II (NHS II), and Health Professionals...

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Identifiers

PMID: 29520861
DOI: 10.1002/gepi.22118
PMCID: PMC5980715

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NHS
MET

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