Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hepatitis B Virus Core Promoter Double Mutations (A1762T, G1764A) Are Associated with Lower Levels of Serum Dihydrolipoyl Dehydrogenase.

Intervirology - 1 Jan 2016

Jiang Zhi-Hua, Chen Qin-Yan, Harrison Tim J, Li Guo-Jian, Wang Xue-Yan, Li Hai, Hu Li-Ping, Li Kai-Wen, Yang Qing-Li, Tan Chao, Fang Zhong-Liao

Abstract excerpt

OBJECTIVES: The aim of this study was to identify serum proteins with differential concentrations between hepatocellular carcinoma (HCC) patients and HBsAg asymptomatic carriers among individuals infected with hepatitis B virus (HBV) with basal core promoter (BCP) double mutations (A1762T, G1764A). METHODS: iTRAQ and liquid chromatography-tandem mass spectrometry were used to identify differentially expressed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asymptomatic Infections
Share to Dihydrolipoamide Dehydrogenase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B

Share to Hepatitis B, Chronic

Share to Hepatitis B Surface Antigens

Share to Proteomics

Share to Tandem Mass Spectrometry

Share to Viral Core Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 27303803
DOI: 10.1159/000445319
PMCID: PMC5079069

Genes

DLD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hepatitis B Virus Core Promoter Double Mutations (A1762T, G1764A) Are Associated with Lower Levels of Serum Dihydrolipoyl Dehydrogenase.PMID 27303803Read ↗

Naturally occurring basal core promoter A1762T/G1764A dual mutations increase the risk of HBV-related hepatocellular carcinoma: a meta-analysis.Semantic proximity Read ↗

The association of HBV core promoter double mutations (A1762T and G1764A) with viral load differs between HBeAg positive and anti-HBe positive individuals: a longitudinal analysis.Semantic proximity Read ↗

The incidence rate over 10 years of naturally occurring, cancer related mutations in the basal core promoter of hepatitis B virus.Semantic proximity Read ↗

[Association of circulating levels of soluble PD-1, PD-1 gene polymorphisms with HBV infection and HBV infection-associated hepatocellular carcinoma].Semantic proximity Read ↗

T1764G1766 core promoter double mutants are restricted to Hepatitis B virus strains with an A1757 and are common in genotype D.Semantic proximity Read ↗

Comparative Analysis of Serum Proteins Between Hepatitis B Virus Genotypes B and C Infection by DIA-Based Quantitative ProteomicsSemantic proximity Read ↗

A1762T/G1764A mutations of hepatitis B virus, associated with the increased risk of hepatocellular carcinoma, reduce basal core promoter activities.Semantic proximity Read ↗

[Significance of the double mutations of C1673T/C1799G in HBV C promoter].Semantic proximity Read ↗

Virological and clinical implication of core promoter C1752/V1753 and T1764/G1766 mutations in hepatitis B virus genotype D infection in Mongolia.Semantic proximity Read ↗

Variations in DEPDC5 gene and its association with chronic hepatitis C virus infection in Saudi Arabia.Semantic proximity Read ↗

Des-γ carboxyprothrombin may not be a good biomarker for hepatocellular carcinoma in those chronically infected with hepatitis B virus with basal core promoter double mutations (T^{1762}, A^{1764}), a prospective study.Semantic proximity Read ↗

Proteomic analysis of cellular protein alterations using a hepatitis B virus‐producing cellular modelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.