Article
Des-γ carboxyprothrombin may not be a good biomarker for hepatocellular carcinoma in those chronically infected with hepatitis B virus with basal core promoter double mutations (T^{1762}, A^{1764}), a prospective study.
Cancer biomarkers : section A of Disease markers - 1 Jan 2017
Li Guo-Jian, Chen Qin-Yan, Harrison Tim J, Wang Xue-Yan, Hu Li-Ping, Yang Qing-Li, Li Kai-Wen, Fang Zhong-Liao
Abstract excerpt
BACKGROUND: The accuracy of des-γ -carboxyprothrombin (DCP) in the detection of hepatocellular carcinoma (HCC) in those infected hepatitis B virus (HBV) from cross-sectional or case-control studies is contradictory. OBJECTIVE: To resolve this contradiction using a prospective study. METHODS: Three hundred male individuals persistently infected with HBV were recruited from the Chinese cohort and followed up once...
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