Article
Manipulation of a Single Circulating Tumor Cell Using Visualization of Hydrogel Encapsulation toward Single-Cell Whole-Genome Amplification.
Analytical chemistry - 19 Jul 2016
Yoshino Tomoko, Tanaka Tsuyoshi, Nakamura Seita, Negishi Ryo, Hosokawa Masahito, Matsunaga Tadashi
Abstract excerpt
Genetic characterization of circulating tumor cells (CTCs) could guide the choice of therapies for individual patients and also facilitate the development of new drugs. We previously developed a CTC recovery system using a microcavity array, which demonstrated highly efficient CTC recovery based on differences in cell size and deformability. However, the CTC recovery system lacked an efficient cell manipulation...
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