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Article

Generation of functional podocytes from human induced pluripotent stem cells

3 Jun 2016

Abstract excerpt

Generating human podocytes in vitro could offer a unique opportunity to study human diseases. Here, we describe a simple and efficient protocol for obtaining functional podocytes in vitro from human induced pluripotent stem cells. Cells were exposed to a three-step protocol, which induced their differentiation into intermediate mesoderm, then into nephron progenitors and, finally, into mature podocytes. After...

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PMID: 27299470
DOI: 10.1016/j.scr.2016.06.001

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