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The Directed Differentiation of Human iPS Cells into Kidney Podocytes

28 Sept 2012

Abstract excerpt

The loss of glomerular podocytes is a key event in the progression of chronic kidney disease resulting in proteinuria and declining function. Podocytes are slow cycling cells that are considered terminally differentiated. Here we provide the first report of the directed differentiation of induced pluripotent stem (iPS) cells to generate kidney cells with podocyte features. The iPS-derived podocytes share a...

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PMID: 23029522
DOI: 10.1371/journal.pone.0046453

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