Integrated mate-pair and RNA sequencing identifies novel, targetable gene fusions in peripheral T-cell lymphoma

Abstract excerpt

Peripheral T-cell lymphomas (PTCLs) represent a heterogeneous group of T-cell malignancies that generally demonstrate aggressive clinical behavior, often are refractory to standard therapy, and remain significantly understudied. The most common World Health Organization subtype is PTCL, not otherwise specified (NOS), essentially a "wastebasket" category because of inadequate understanding to assign cases to a...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Lymphoma Diagnosis and Treatment
• Share to T-cell and Retrovirus Studies
• Share to Ubiquitin and proteasome pathways