Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

EGFR and KRAS mutational analysis and their correlation to survival in pancreatic and periampullary cancer.

Pancreas - 1 Apr 2012

Oliveira-Cunha Melissa, Hadfield Kristen D, Siriwardena Ajith K, Newman William

Abstract excerpt

OBJECTIVES: Pancreatic and periampullary cancers have a high incidence of activating KRAS mutations. The aim of this study was to determine the incidence of KRAS and EGFR mutations in pancreatic and periampullary cancers and their relationship with survival. METHODS: One hundred patients undergoing pancreaticoduodenectomy or pancreatic biopsy for cancer were recruited. Samples of formalin-fixed paraffin-embedded...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biopsy
Share to Codon
Share to Digestive System Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to England

Share to Kaplan-Meier Estimate

Share to Pancreatic Neoplasms

Share to Proto-Oncogene Proteins p21(ras)

Share to ras Proteins

Source

Identifiers

PMID: 22422135
DOI: 10.1097/MPA.0b013e3182327a03

Genes

KRAS
EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

EGFR and KRAS mutational analysis and their correlation to survival in pancreatic and periampullary cancer.PMID 22422135Read ↗

Somatic Mutations in Exocrine Pancreatic Tumors: Association with Patient SurvivalSemantic proximity Read ↗

Impact of KRAS mutations on clinical outcomes in pancreatic cancer patients treated with first-line gemcitabine-based chemotherapy.Semantic proximity Read ↗

KRAS, BRAF, and PIK3CA mutations, and patient prognosis in 126 pancreatic cancers: pyrosequencing technology and literature review.Semantic proximity Read ↗

Impact of epidermal growth factor receptor (EGFR) kinase mutations, EGFR gene amplifications, and KRAS mutations on survival of pancreatic adenocarcinoma.Semantic proximity Read ↗

Frequencies and prognostic role of KRAS and BRAF mutations in patients with localized pancreatic and ampullary adenocarcinomas.Semantic proximity Read ↗

Prognostic value of KRAS gene mutations in pancreatic ductal adenocarcinoma: a systematic review and meta-analysis.Semantic proximity Read ↗

Survival in ampullary cancer: potential role of different KRAS mutations.Semantic proximity Read ↗

The Clinical Implications of KRAS Mutations and Variant Allele Frequencies in Pancreatic Ductal AdenocarcinomaSemantic proximity Read ↗

KRAS mutation in pancreatic cancer.Semantic proximity Read ↗

KRAS variant allele frequency, but not mutation positivity, associates with survival of patients with pancreatic cancer.Semantic proximity Read ↗

Targeting KRAS in pancreatic cancer.Semantic proximity Read ↗

Impact of KRAS Mutations and Co-mutations on Clinical Outcome in Pancreatic Ductal AdenocarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.