Article
Risk of non-melanoma cancers in first-degree relatives of CDKN2A mutation carriers.
Journal of the National Cancer Institute - 20 Jun 2012
Mukherjee Bhramar, Delancey John Oliver, Raskin Leon, Everett Jessica, Jeter Joanne, Begg Colin B, Orlow Irene, Berwick Marianne, Armstrong Bruce K, Kricker Anne, Marrett Loraine D, Millikan Robert C, Culver Hoda Anton, Rosso Stefano, Zanetti Roberto, Kanetsky Peter A, From Lynn, Gruber Stephen B
Abstract excerpt
The purpose of this study was to quantify the risk of cancers other than melanoma among family members of CDKN2A mutation carriers using data from the Genes, Environment and Melanoma study. Relative risks (RRs) of all non-melanoma cancers among first-degree relatives (FDRs) of melanoma patients with CDKN2A mutations (n = 65) and FDRs of melanoma patients without mutations (n = 3537) were calculated as the ratio...
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