Genetics of familial melanoma: 20 years after <i><scp>CDKN</scp>2<scp>A</scp></i>

Abstract excerpt

Twenty years ago, the first familial melanoma susceptibility gene, CDKN2A, was identified. Two years later, another high-penetrance gene, CDK4, was found to be responsible for melanoma development in some families. Progress in identifying new familial melanoma genes was subsequently slow; however, with the advent of next-generation sequencing, a small number of new high-penetrance genes have recently been...

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