A Five-Gene Molecular Grade Index and <i>HOXB13:IL17BR</i> Are Complementary Prognostic Factors in Early Stage Breast Cancer

Abstract excerpt

PURPOSE: Histologic tumor grade is a well-established prognostic factor for breast cancer, and tumor grade-associated genes are the common denominator of many prognostic gene signatures. The objectives of this study are as follows: (a) to develop a simple gene expression index for tumor grade (molecular grade index or MGI), and (b) to determine whether MGI and our previously described HOXB13:IL17BR index together...

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