Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Biguanides sensitize leukemia cells to ABT-737-induced apoptosis by inhibiting mitochondrial electron transport

6 Jun 2016

Abstract excerpt

// Juliana Velez 1, 2 , Rongqing Pan 6 , Jason T.C. Lee 7 , Leonardo Enciso 2 , Marta Suarez 2 , Jorge Eduardo Duque 3 , Daniel Jaramillo 1 , Catalina Lopez 4 , Ludis Morales 1 , William Bornmann 5 , Marina Konopleva 6 , Gerald Krystal 7 , Michael Andreeff 6 , Ismael Samudio 1, 2, 8 1 Grupo de Terapia Celular y Molecular, Pontificia Universidad Javeriana, Bogotá, Colombia 2 Programa de Investigación...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Metabolism, Diabetes, and Cancer
Share to Pancreatic function and diabetes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27283492
DOI: 10.18632/oncotarget.9843

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Biguanides sensitize leukemia cells to ABT-737-induced apoptosis by inhibiting mitochondrial electron transportPMID 27283492Read ↗

Taxodione induces apoptosis in BCR-ABL-positive cells through ROS generationSemantic proximity Read ↗

Structurally diverse c-Myc inhibitors share a common mechanism of action involving ATP depletionSemantic proximity Read ↗

Enhanced Sensitivity of Nonsmall Cell Lung Cancer with Acquired Resistance to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors to Phenformin: The Roles of a Metabolic Shift to Oxidative Phosphorylation and Redox Balance.Semantic proximity Read ↗

Concentration‐dependent metabolic effects of metformin in healthy and Fanconi anemia lymphoblast cellsSemantic proximity Read ↗

2-Methoxy antimycin reveals a unique mechanism for Bcl-x(L) inhibition.Semantic proximity Read ↗

Methanolic extract of Moringa oleifera leaves induces Cell cycle arrest and downregulates Mitochondrial membrane potential in Dalton's Lymphoma cells.Semantic proximity Read ↗

Phenformin increases early hematopoietic progenitors in the Jak2V617F murine model.Semantic proximity Read ↗

L503F variant of carnitine/organic cation transporter 1 efficiently transports metformin and other biguanides.Semantic proximity Read ↗

Mitochondrial electron transport is the cellular target of the oncology drug elesclomol.Semantic proximity Read ↗

Fucoxanthin induces apoptosis in acute lymphoblastic leukaemia cell line by damaging the endoplasmic reticulumSemantic proximity Read ↗

Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis.Semantic proximity Read ↗

L-Carnitine protects against methotrexate-induced hepatotoxicity via regulation of apoptosis and metabolic pathwaysSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.