Article
Adult human megakaryocyte-erythroid progenitors are in the CD34+CD38mid fraction.
Blood - 18 Aug 2016
Sanada Chad, Xavier-Ferrucio Juliana, Lu Yi-Chien, Min Elizabeth, Zhang Ping-Xia, Zou Siying, Kang Elaine, Zhang Meng, Zerafati Gazelle, Gallagher Patrick G, Krause Diane S
Abstract excerpt
Bipotent megakaryocyte/erythroid progenitors (MEPs) give rise to progeny limited to the megakaryocyte (Mk) and erythroid (E) lineages. We developed a novel dual-detection functional in vitro colony-forming unit (CFU) assay for single cells that differentiates down both the Mk and E lineages (CFU-Mk/E), which allowed development and validation of a novel purification strategy for the identification and...
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