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Article

Siaα2-3Galβ1- Receptor Genetic Variants Are Associated with Influenza A(H1N1)pdm09 Severity.

PloS one - 1 Jan 2015

Maestri Alvino, Sortica Vinicius Albuquerque, Tovo-Rodrigues Luciana, Santos Mirleide Cordeiro, Barbagelata Luana, Moraes Milene Raiol, Alencar de Mello Wyller, Gusmão Leonor, Sousa Rita Catarina Medeiros, Emanuel Batista Dos Santos Sidney

Abstract excerpt

Different host genetic variants may be related to the virulence and transmissibility of pandemic Influenza A(H1N1)pdm09, influencing events such as binding of the virus to the entry receptor on the cell of infected individuals and the host immune response. In the present study, two genetic variants of the ST3GAL1 gene, which encodes the Siaα2-3Galβ1- receptor to which influenza A(H1N1)pdm09 virus binds for entry...

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Identifiers

PMID: 26436774
DOI: 10.1371/journal.pone.0139681
PMCID: PMC4593567

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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