Article
A functional variation in CD55 increases the severity of 2009 pandemic H1N1 influenza A virus infection.
The Journal of infectious diseases - 15 Aug 2012
Zhou Jie, To Kelvin Kai-Wang, Dong Hui, Cheng Zhong-Shan, Lau Candy Choi-Yi, Poon Vincent K M, Fan Yan-Hui, Song You-Qiang, Tse Herman, Chan Kwok-Hung, Zheng Bo-Jian, Zhao Guo-Ping, Yuen Kwok-Yung
Abstract excerpt
Infection due to 2009 pandemic H1N1 influenza A virus (A[H1N1]pdm09) is commonly manifested as mild infection but occasionally as severe pneumonia. We hypothesized that host genetic variations may contribute to disease severity. An initially small-scale genome-wide association study guided the se...
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