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Article

Pharmacogenetics of Antidepressants

1 Jan 2011

Abstract excerpt

Up to 60% of depressed patients do not respond completely to antidepressants (ADs) and up to 30% do not respond at all. Genetic factors contribute for about 50% of the AD response. During the recent years the possible influence of a set of candidate genes as genetic predictors of AD response efficacy was investigated by us and others. They include the cytochrome P450 superfamily, the P-glycoprotein (ABCB1), the...

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PMID: 21687501
DOI: 10.3389/fphar.2011.00006

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