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Article

PGRMC1 participates in late events of bovine granulosa cells mitosis and oocyte meiosis

4 Jun 2016

Abstract excerpt

Progesterone Receptor Membrane Component 1 (PGRMC1) is expressed in both oocyte and ovarian somatic cells, where it is found in multiple cellular sub-compartments including the mitotic spindle apparatus. PGRMC1 localization in the maturing bovine oocytes mirrors its localization in mitotic cells, suggesting a possible common action in mitosis and meiosis. To test the hypothesis that altering PGRMC1 activity leads...

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PMID: 27260975
DOI: 10.1080/15384101.2016.1192731

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