Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Novel Role for Progesterone and Progesterone Receptor Membrane Component 1 in Regulating Spindle Microtubule Stability During Rat and Human Ovarian Cell Mitosis

8 Dec 2010

Abstract excerpt

The present studies were designed to assess the roles of progesterone (P4) and Progesterone Receptor Membrane Component 1 (PGRMC1) in regulating mitosis of spontaneously immortalized granulosa cells (SIGCs) and ovarian cancer cells, SKOV-3 cells. Because PGRMC1 has been detected among the proteins of the human mitotic spindle, we theorized that P4 and PGRMC1 could affect mitosis through a microtubule-dependent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 14-3-3 protein interactions
Share to Microtubule and mitosis dynamics
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21148105
DOI: 10.1095/biolreprod.110.088385

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

A Novel Role for Progesterone and Progesterone Receptor Membrane Component 1 in Regulating Spindle Microtubule Stability During Rat and Human Ovarian Cell MitosisPMID 21148105Read ↗

PGRMC1 participates in late events of bovine granulosa cells mitosis and oocyte meiosisSemantic proximity Read ↗

Progesterone receptor membrane component 1 expression and putative function in bovine oocyte maturation, fertilization, and early embryonic developmentSemantic proximity Read ↗

CDK-1 Inhibition in G2 Stabilizes Kinetochore-Microtubules in the following MitosisSemantic proximity Read ↗

Progesterone Activates a Progesterone Receptor Membrane Component 1-Dependent Mechanism That Promotes Human Granulosa/Luteal Cell Survival But Not Progesterone SecretionSemantic proximity Read ↗

DNA Replication Licensing and Progenitor Numbers Are Increased by Progesterone in Normal Human BreastSemantic proximity Read ↗

Non-Genomic Actions of Progesterone in the Normal and Neoplastic Mammalian OvarySemantic proximity Read ↗

Localization and role of RAP55/LSM14 in HeLa cells: a new finding on the mitotic spindle assembly.Semantic proximity Read ↗

Alterations in progesterone receptor membrane component 2 (PGRMC2) in the endometrium of macaques afflicted with advanced endometriosisSemantic proximity Read ↗

p100: A Novel Proliferation-Associated Nuclear Protein Specifically Restricted to Cell Cycle Phases S, G2 , and MSemantic proximity Read ↗

Advances in uterine leiomyoma research: the progesterone hypothesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.