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Article

A Longitudinal Motor Characterisation of the HdhQ111 Mouse Model of Huntington's Disease.

Journal of Huntington's disease - 31 May 2016

Yhnell Emma, Dunnett Stephen B, Brooks Simon P

Abstract excerpt

BACKGROUND: Huntington's disease (HD) is a rare, incurable neurodegenerative disorder caused by a CAG trinucleotide expansion with the first exon of the huntingtin gene. Numerous knock-in mouse models are currently available for modelling HD. However, before their use in scientific research, these models must be characterised to determine their face and predictive validity as models of the disease and their...

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Identifiers

PMID: 27258586
DOI: 10.3233/JHD-160191
PMCID: PMC4942729

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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