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Article

Analysis of the GCK gene in 79 MODY type 2 patients: A multicenter Turkish study, mutation profile and description of twenty novel mutations.

Gene - 30 Jan 2018

Aykut Ayça, Karaca Emin, Onay Hüseyin, Gökşen Damla, Çetinkalp Şevki, Eren Erdal, Ersoy Betül, Çakır Esra Papatya, Büyükinan Muammer, Kara Cengiz, Anık Ahmet, Kırel Birgül, Özen Samim, Atik Tahir, Darcan Şükran, Özkınay Ferda

Abstract excerpt

Maturity onset diabetes is a genetic form of diabetes mellitus characterized by an early age at onset and several etiologic genes for this form of diabetes have been identified in many patients. Maturity onset diabetes type 2 [MODY2 (#125851)] caused by mutations in the glucokinase gene (GCK). Although its prevalence is not clear, it is estimated that 1%-2% of patients with diabetes have the monogenic form. The...

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Identifiers

PMID: 29056535
DOI: 10.1016/j.gene.2017.10.057

Genes

GCK

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of the GCK gene in 79 MODY type 2 patients: A multicenter Turkish study, mutation profile and description of twenty novel mutations.PMID 29056535Read ↗

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