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Article

Hemoglobin A1C can differentiate subjects with GCK mutations among patients suspected to have MODY.

Journal of pediatric endocrinology & metabolism : JPEM - 16 Dec 2022

Yılmaz Uzman Ceren, Erbaş İbrahim Mert, Giray Bozkaya Özlem, Paketçi Ahu, Çağlayan Ahmet Okay, Abacı Ayhan, Kulalı Melike Ataseven, Böber Ece, Kekilli Arda, Çinleti Tayfun, Erçal Murat Derya, Demir Korcan

Abstract excerpt

OBJECTIVES: The aim of this study is to determine the clinical and molecular characteristics enabling differential diagnosis in a group of Turkish children clinically diagnosed with MODY and identify the cut-off value of HbA1c, which can distinguish patients with GCK variants from young-onset type 1 and type 2 diabetes. METHODS: The study included 49 patients from 48 unrelated families who were admitted between...

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PMID: 36197956
DOI: 10.1515/jpem-2022-0381

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