Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Infiltrating immune cells and gene mutations in pancreatic ductal adenocarcinoma.

The British journal of surgery - 1 Aug 2016

Wang W-Q, Liu L, Xu H-X, Wu C-T, Xiang J-F, Xu J, Liu C, Long J, Ni Q-X, Yu X-J

Abstract excerpt

BACKGROUND: The aim of this study was to assess the immune profile within the microenvironment of pancreatic ductal adenocarcinoma (PDAC), and to investigate the prognostic value of intratumoral infiltrating immune/inflammatory cells (IICs) in patients after surgery. METHODS: Eighteen phenotypic markers representing 11 types of IIC and the protein products of genes TP53, CDKN2A/p16 and SMAD4/DPC4 were assessed by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Pancreatic Ductal
Share to Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Recurrence, Local

Share to Neutrophil Infiltration

Share to Neutrophils

Share to Pancreatic Neoplasms

Share to Survival Analysis

Share to Tumor Microenvironment

Source

Identifiers

PMID: 27256393
DOI: 10.1002/bjs.10187

Genes

SMAD4
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Infiltrating immune cells and gene mutations in pancreatic ductal adenocarcinoma.PMID 27256393Read ↗

Comparative Immune profiling in Pancreatic Ductal Adenocarcinoma Progression Among South African patientsSemantic proximity Read ↗

Stratification of Pancreatic Ductal Adenocarcinoma: Combinatorial Genetic, Stromal, and Immunologic Markers.Semantic proximity Read ↗

The reciprocal regulation between host tissue and immune cells in pancreatic ductal adenocarcinoma: new insights and therapeutic implicationsSemantic proximity Read ↗

Keratin 17 modulates the immune topography of pancreatic cancerSemantic proximity Read ↗

Intra-Tumoral CD8+ T-Cell Infiltration and PD-L1 Positivity in Homologous Recombination Deficient Pancreatic Ductal AdenocarcinomaSemantic proximity Read ↗

Tumor immune-gene expression profiles and peripheral immune phenotypes associated with clinical outcomes of locally advanced pancreatic cancer following FOLFIRINOX.Semantic proximity Read ↗

Tumor-intrinsic MHC-II activation in pancreatic ductal adenocarcinoma enhances immune response and treatment efficacySemantic proximity Read ↗

S100P as a potential biomarker for immunosuppressive microenvironment in pancreatic cancer: a bioinformatics analysis and in vitro studySemantic proximity Read ↗

Topographical Distribution and Spatial Interactions of Innate and Semi-Innate Immune Cells in Pancreatic and Other Periampullary Adenocarcinoma.Semantic proximity Read ↗

M2-phenotype tumour-associated macrophages upregulate the expression of prognostic predictors MMP14 and INHBA in pancreatic cancer.Semantic proximity Read ↗

Composition, Spatial Characteristics, and Prognostic Significance of Myeloid Cell Infiltration in Pancreatic CancerSemantic proximity Read ↗

The role of inflammatory cells in fostering pancreatic cancer cell growth and invasionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.