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Article

The role of inflammatory cells in fostering pancreatic cancer cell growth and invasion

1 Jan 2012

Abstract excerpt

The pancreatic ductal adenocarcinoma (PDAC) microenvironment accommodates a variety of cell types and a plethora of complex interactions between tumor cells, host cells and extracellular matrix (ECM) components. Here we review the role of inflammatory cells, in particular mast cells, myeloid-derived suppressor cells, macrophages, T regulatory cells, T helper cells and neutrophils. The picture that emerges is that...

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Identifiers

PMID: 22969725
DOI: 10.3389/fphys.2012.00270

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