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Article

Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation

2 Jun 2016

Abstract excerpt

Identifying host immune determinants governing HIV transcription, latency and infectivity in vivo is critical to developing an HIV cure. Based on our recent finding that the host factor p21 regulates HIV transcription during antiretroviral therapy (ART), and published data demonstrating that the human carbohydrate-binding immunomodulatory protein galectin-9 regulates p21, we hypothesized that galectin-9 modulates...

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PMID: 27253379
DOI: 10.1371/journal.ppat.1005677

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