Article
Frequency of Tabagism and N34S and P55S Mutations of Serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) and R254W Mutation of Chymotrypsin C (CTRC) in Patients With Chronic Pancreatitis and Controls.
Pancreas - 1 Oct 2016
da Costa Marianges Zadrozny Gouvêa, Pires Júlia Glória Lucatelli, Nasser Paulo Dominguez, Ferreira Camila da Silva, Teixeira Ana Cristina de Sá, Paranaguá-Vezozzo Denise Cerqueira, Guarita Dulce Reis, Carrilho Flair José, Ono Suzane Kioko
Abstract excerpt
OBJECTIVE: This study aimed to investigate the association between chronic pancreatitis and smoking or genetic mutations. METHODS: The study sample comprised 148 patients with chronic pancreatitis, 110 chronic alcoholic subjects without pancreatic disease, and 297 volunteer blood donors. RESULTS: Of the patients with chronic pancreatitis, 74% had alcoholic etiology and 26% had idiopathic pancreatitis. The...
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