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Application of next-generation sequencing in clinical oncology to advance personalized treatment of cancer.

Chinese journal of cancer - 1 Oct 2012

Guan Yan-Fang, Li Gai-Rui, Wang Rong-Jiao, Yi Yu-Ting, Yang Ling, Jiang Dan, Zhang Xiao-Ping, Peng Yin

Abstract excerpt

With the development and improvement of new sequencing technology, next-generation sequencing (NGS) has been applied increasingly in cancer genomics research over the past decade. More recently, NGS has been adopted in clinical oncology to advance personalized treatment of cancer. NGS is used to identify novel and rare cancer mutations, detect familial cancer mutation carriers, and provide molecular rationale for...

Topics

High-Throughput Nucleotide Sequencing
Humans
Mutation
Neoplasms
Precision Medicine
Sequence Analysis, DNA

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 22980418
DOI: 10.5732/cjc.012.10216
PMCID: PMC3777453

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