Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ESCRT-II controls retinal axon growth by regulating DCC receptor levels and local protein synthesis.

Open biology - 1 Apr 2016

Konopacki Filip A, Wong Hovy Ho-Wai, Dwivedy Asha, Bellon Anaïs, Blower Michael D, Holt Christine E

Abstract excerpt

Endocytosis and local protein synthesis (LPS) act coordinately to mediate the chemotropic responses of axons, but the link between these two processes is poorly understood. The endosomal sorting complex required for transport (ESCRT) is a key regulator of cargo sorting in the endocytic pathway, and here we have investigated the role of ESCRT-II, a critical ESCRT component, in Xenopus retinal ganglion cell (RGC)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DCC Receptor
Share to Endosomal Sorting Complexes Required for Transport

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endosomes

Share to Growth Cones

Share to Nerve Growth Factors

Share to Netrin-1

Share to Retinal Ganglion Cells

Share to Xenopus Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 27248654
DOI: 10.1098/rsob.150218
PMCID: PMC4852451

Genes

DCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ESCRT-II controls retinal axon growth by regulating DCC receptor levels and local protein synthesis.PMID 27248654Read ↗

Netrin-1 and DCC mediate axon guidance locally at the optic disc: loss of function leads to optic nerve hypoplasia.Semantic proximity Read ↗

Melanopsin regulates axonal translation underlying retinohypothalamic circuit assemblySemantic proximity Read ↗

Subcellular transcriptome of radial glia reveals compartmentalized control of cortical developmentSemantic proximity Read ↗

Presenilin-dependent receptor processing is required for axon guidance.Semantic proximity Read ↗

Human Retinal Ganglion Cells Respond to Evolutionarily Conserved Chemotropic Cues for Intra Retinal Guidance and RegenerationSemantic proximity Read ↗

Peripheral axonal ensheathment is regulated by RalA GTPase and the exocyst complex.Semantic proximity Read ↗

Sortilin regulates sorting and secretion of Sonic hedgehog.Semantic proximity Read ↗

Netrin-DCC, Robo-Slit, and heparan sulfate proteoglycans coordinate lateral positioning of longitudinal dopaminergic diencephalospinal axons.Semantic proximity Read ↗

Draxin Inhibits Axonal Outgrowth through the Netrin Receptor DCCSemantic proximity Read ↗

Subcellular mRNA localization and local translation of <i>Arhgap11a</i> in radial glial cells regulates cortical developmentSemantic proximity Read ↗

Drosophila JAB1/CSN5 acts in photoreceptor cells to induce glial cells.Semantic proximity Read ↗

Netrin/DCC signaling guides olfactory sensory axons to their correct location in the olfactory bulb.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.