Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ribosome quality control is a central protection mechanism for yeast exposed to deoxynivalenol and trichothecin.

BMC genomics - 1 Jun 2016

Kugler Karl G, Jandric Zeljkica, Beyer Reinhard, Klopf Eva, Glaser Walter, Lemmens Marc, Shams Mehrdad, Mayer Klaus, Adam Gerhard, Schüller Christoph

Abstract excerpt

BACKGROUND: The trichothecene mycotoxins deoxynivalenol (DON) and trichothecin (TTC) are inhibitors of eukaryotic protein synthesis. Their effect on cellular homeostasis is poorly understood. We report a systematic functional investigation of the effect of DON and TTC on the yeast Saccharomyces cerevisiae using genetic array, network and microarray analysis. To focus the genetic analysis on intracellular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin Assembly and Disassembly
Share to Drug Resistance, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epistasis, Genetic

Share to Gene Knockdown Techniques

Share to Gene Regulatory Networks

Share to Ribosomes

Share to Trichothecenes

Share to Yeasts

Source

Open in PubMed Open full text

Identifiers

PMID: 27245696
DOI: 10.1186/s12864-016-2718-y
PMCID: PMC4888481

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ribosome quality control is a central protection mechanism for yeast exposed to deoxynivalenol and trichothecin.PMID 27245696Read ↗

Saccharomyces cerevisae and Arabidopsis thaliana: useful model systems for the identification of molecular mechanisms involved in resistance of plants to toxinsSemantic proximity Read ↗

Mitochondrial ribosomal proteins involved in tellurite resistance in yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Comprehensive gene expression analysis of type B trichothecenes.Semantic proximity Read ↗

A genome-wide deletion mutant screen identifies pathways affected by nickel sulfate in Saccharomyces cerevisiae.Semantic proximity Read ↗

Ribosomal Dysfunction Is a Common Pathomechanism in Different Forms of Trichothiodystrophy.Semantic proximity Read ↗

The thioredoxin system protects ribosomes against stress-induced aggregation.Semantic proximity Read ↗

Impairment of ribosomes and DNA biosynthesis confers resistance to Inhibition of sphingolipid biosynthesis.Semantic proximity Read ↗

The Toxicity of a Novel Antifungal Compound Is Modulated by Endoplasmic Reticulum-Associated Protein Degradation Components.Semantic proximity Read ↗

A chemical genomic screen in Saccharomyces cerevisiae reveals a role for diphthamidation of translation elongation factor 2 in inhibition of protein synthesis by sordarin.Semantic proximity Read ↗

Saccharomyces cerevisiae Elongator mutations confer resistance to the Kluyveromyces lactis zymocin.Semantic proximity Read ↗

Transcriptome profiling of a Saccharomyces cerevisiae mutant with a constitutively activated Ras/cAMP pathway.Semantic proximity Read ↗

Yeast as a Heterologous Model System to Uncover Type III Effector Function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.