Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between domestic water hardness, chlorine, and atopic dermatitis risk in early life: A population-based cross-sectional study.

The Journal of allergy and clinical immunology - 1 Aug 2016

Perkin Michael R, Craven Joanna, Logan Kirsty, Strachan David, Marrs Tom, Radulovic Suzana, Campbell Linda E, MacCallum Stephanie F, McLean W H Irwin, Lack Gideon, Flohr Carsten

Abstract excerpt

BACKGROUND: Domestic water hardness and chlorine have been suggested as important risk factors for atopic dermatitis (AD). OBJECTIVE: We sought to examine the link between domestic water calcium carbonate (CaCO3) and chlorine concentrations, skin barrier dysfunction (increased transepidermal water loss), and AD in infancy. METHODS: We recruited 1303 three-month-old infants from the general population and gathered...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chlorine
Share to Dermatitis, Atopic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Filaggrin Proteins

Share to Intermediate Filament Proteins

Share to Maternal Exposure

Share to Population Surveillance

Share to Prenatal Exposure Delayed Effects

Source

Identifiers

PMID: 27241890
DOI: 10.1016/j.jaci.2016.03.031

Genes

FLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between domestic water hardness, chlorine, and atopic dermatitis risk in early life: A population-based cross-sectional study.PMID 27241890Read ↗

The Effect of Water Hardness on Surfactant Deposition after Washing and Subsequent Skin Irritation in Atopic Dermatitis Patients and Healthy Control Subjects.Semantic proximity Read ↗

Frequent oil baths and skin barrier during infancy in the PreventADALL study.Semantic proximity Read ↗

Atopic dermatitis and disease severity are the main risk factors for food sensitization in exclusively breastfed infants.Semantic proximity Read ↗

Skin barrier dysfunction measured by transepidermal water loss at 2 days and 2 months predates and predicts atopic dermatitis at 1 year.Semantic proximity Read ↗

Transepidermal water loss measurement during infancy can predict the subsequent development of atopic dermatitis regardless of filaggrin mutations.Semantic proximity Read ↗

Comprehending Atopic Risk Elements (CARE): An observational study to determine lifestyle, biophysical and environmental risk factors in the development of early-onset pediatric atopic dermatitisSemantic proximity Read ↗

Neonatal urinary phthalate metabolite concentrations predict the development of atopic dermatitisSemantic proximity Read ↗

Water hardness and a possible genetic link with eczema in children.Semantic proximity Read ↗

Children with atopic dermatitis and frequent emollient use have increased urinary levels of low-molecular-weight phthalate metabolites and parabens.Semantic proximity Read ↗

Early-life regional and temporal variation in filaggrin-derived natural moisturizing factor, filaggrin-processing enzyme activity, corneocyte phenotypes and plasmin activity: implications for atopic dermatitis.Semantic proximity Read ↗

Atopic dermatitis and risk factors in poor children from Great Buenos Aires, Argentina.Semantic proximity Read ↗

The association between phthalate exposure and atopic dermatitis with a discussion of phthalate induced secretion of interleukin-1β and thymic stromal lymphopoietin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.