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Migration and invasion is inhibited by silencing ROR1 and ROR2 in chemoresistant ovarian cancer

30 May 2016

Abstract excerpt

Ovarian cancer survival remains poor despite recent advances in our understanding of genetic profiles. Unfortunately, the majority of ovarian cancer patients have recurrent disease after chemotherapy and lack other treatment options. Wnt signalling has been extensively implicated in cancer progression and chemoresistance. Therefore, we investigated the previously described Wnt receptors ROR1 and ROR2 as...

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PMID: 27239958
DOI: 10.1038/oncsis.2016.32

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