Article

CD44 mediates hyaluronan to promote the differentiation of human amnionic mesenchymal stem cells into chondrocytes through the activation of Erk1/2 and Smad2 signals

2022-06-29

Abstract excerpt

<title>Abstract</title> <bold>Background:</bold> Hyaluronan (HA), as a major component of the cellular matrix, plays an important role in cartilage formation. Our previous studies showed that HA may induce human amnion mesenchymal stem cells (hAMSCs) to differentiate into chondrocytes. The surface molecule CD44, as the main receptor of hyaluronic acid, is crucial for maintaining cartilage homeostasis. But the...

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Literature Corpus work: a7dad9d6-e43e-5718-8d00-4280d6470edc
DOI: 10.21203/rs.3.rs-1740971/v1

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