Article
Uterine serous carcinoma: Molecular features, clinical management, and new and future therapies.
Gynecologic oncology - 1 Jan 2021
Lee Elizabeth K, Fader Amanda N, Santin Alessandro D, Liu Joyce F
Abstract excerpt
Uterine serous carcinoma (USC) is an aggressive subtype of endometrial cancer. Multimodality treatment with surgery, radiotherapy, and chemotherapy is commonly used, given its propensity for extrauterine spread, distant recurrences, and poor prognosis. However, the use of molecularly-based therapy is expanding. Here, we review key molecular features of USC, discuss current management, and assess the landscape of...
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