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Article

Exosomal cancer immunotherapy is independent of MHC molecules on exosomes.

Oncotarget - 21 Jun 2016

Hiltbrunner Stefanie, Larssen Pia, Eldh Maria, Martinez-Bravo Maria-Jose, Wagner Arnika K, Karlsson Mikael C I, Gabrielsson Susanne

Abstract excerpt

Peptide-loaded exosomes are promising cancer treatment vehicles; however, moderate T cell responses in human clinical trials indicate a need to further understand exosome-induced immunity. We previously demonstrated that antigen-loaded exosomes carry whole protein antigens and require B cells for inducing antigen-specific T cells. Therefore, we investigated the relative importance of exosomal major...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27231849
DOI: 10.18632/oncotarget.9585
PMCID: PMC5122422

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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