Article
Immunostimulatory activity of murine keratinocyte-derived exosomes.
Experimental dermatology - 1 Oct 2013
Kotzerke Kristina, Mempel Martin, Aung Thiha, Wulf Gerald G, Urlaub Henning, Wenzel Dirk, Schön Michael P, Braun Andrea
Abstract excerpt
It has long been known that keratinocytes influence cutaneous immunity through secretion of soluble factors. Exosomes, small membrane vesicles of endocytotic origin, have been implicated in intercellular communication processes such as the transfer of tumor cell antigens and the activation of recipient dendritic cells (DC). However, little is known about immunomodulatory functions of keratinocyte-derived...
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